Abnormal Spontaneous Neural Activity in Parkinson’s Disease With “pure” Apathy
نویسندگان
چکیده
منابع مشابه
Parkinsons Disease Classification using Neural Network and Feature Selection
In this study, the Multi-Layer Perceptron (MLP)with Back-Propagation learning algorithm are used to classify to effective diagnosis Parkinsons disease(PD).It’s a challenging problem for medical community.Typically characterized by tremor, PD occurs due to the loss of dopamine in the brains thalamic region that results in involuntary or oscillatory movement in the body. A feature selection algor...
متن کاملAbnormal spontaneous neural activity in the anterior insular and anterior cingulate cortices in anxious depression.
OBJECTIVE Anxious depression is a distinct clinical subtype of major depressive disorder (MDD) characterized by palpitations, somatic complaints, altered interoceptive awareness, high risk of suicide, and poor response to pharmacotherapy. However, the neural mechanisms of anxious depression are still not well understood. In this study we investigated changes in neural oscillation during the res...
متن کاملAbnormal Spontaneous Neural Activity in Obsessive-Compulsive Disorder: A Resting-State Functional Magnetic Resonance Imaging Study
Neuroimaging studies of obsessive-compulsive disorder have found abnormalities in orbitofronto-striato-thalamic circuitry, including the orbitofrontal cortex, anterior cingulate cortex, caudate, and thalamus, but few studies have explored abnormal intrinsic or spontaneous brain activity in the resting state. We investigated both intra- and inter-regional synchronized activity in twenty patients...
متن کاملApathy in Alzheimer's disease
Apathy is the most common neuropsychiatric symptom in patients with Alzheimer’s disease (AD). The presence of apathy has been related to greater caregiver distress, decreased quality of life, and increased morbidity. Here we review the most recent studies on this neuropsychiatric syndrome, focusing on prevalence, impact on quality of life, behavioural and neuroimaging studies, and treatment opt...
متن کاملApathy in Alzheimer's disease
In the last few years, a growing number of studies have been devoted to affective disturbances in Alzheimer disease, AD. These studies showed that apathy is a symptom clearly distinct from depression, and that confusion between apathy and depression appears to be one major cause of variability in the assessment of the frequency of depression in AD. We present the results of four studies from ou...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2020
ISSN: 1662-453X
DOI: 10.3389/fnins.2020.00830